一、个人简介

        博士，二级教授，博士生导师。四川省高层次引进人才“千人计划”学者，四川省学术和技术带头人。清华大学毕业获得生物学博士学位，美国加州大学圣地亚哥分校进行博士后研究工作。曾任清华大学医学院研究员，博士生导师。

        研究方向为中医药分子肿瘤学，主要关注中西医结合抗肿瘤的分子机制及药物发现。相关研究工作以通讯作者或第一作者在Nature、Nature Structural & Molecular Biology、Science Advances、Cell Research、Nucleic Acids Research等国际知名刊物发表，其中2篇入选全球top 1%高被引论文，单篇最高引用次数>900。申请美国和中国专利18项，授权11项，转化1项。主持教育部生物治疗协同创新中心、自然科学基金委（3项）、北京市首都健康培育项目、四川省天府英才工程等多个项目。现任中国医药教育协会健康管理专委会副主任委员，中国抗癌协会肿瘤转移专业委员会委员，BMC Cancer等3个国际SCI刊物编委。

二、代表性成果

    1.  Yifei Dai, Weijie Qiang, Yu Gui, Xue Tan, Tianli Pei, Kequan Lin, Siwei Cai, Liang Sun, Guochen Ning, Jianxun Wang, Hongyan Guo, Yimin Sun, Jing Cheng, Lan Xie*, Xun Lan*, Dong Wang*. A large-scale transcriptional study reveals inhibition of COVID-19 related cytokine storm by traditional Chinese medicines. Science Bulletin, 2021, 66(9):884-888. （影响因子20.577）

    2.  Huili Wang，Kequan Lin, Lin Zhu, Shaojun Zhang, Le Li, Yilie Liao, Baichao Zhang, Ming    Yang, Xinde Liu, Lu Li, Shasha Li, Liuqing Yang, Haiyan Wang, Qianyu Wang, Haitao Li, Suneng Fu, Xiaorong Zhang, Peng Jiang, Qiangfeng Cliff Zhang, Jing Cheng*, Dong Wang*. Oncogenic lncRNA LINC00973 promotes warburg effect by enhancing LDHA enzyme activity. Science Bulletin, 2021, 66(13):1330-1334 （影响因子20.577）

    3.  Haiyan Wang, Shasha Li, Qianyu Wang, Zhenshuo Jin, Wei Shao, Yan Gao, Lu Li, Kequan Lin, Lin Zhu, Huili Wang, Xuebin Liao, Dong Wang*. Tumor immunological phenotype signature-based high-throughput screening for the discovery of combination immunotherapy compounds. Science Advances. 7, eabd7851, 2021 （影响因子14.957）

    4.  Shuaishuai Teng, Yang Eric Li, Ming Yang, Rui Qi, Yiming Huang, Qianyu Wang, Yanmei Zhang, Shanwen Chen, Shasha Li, Kequan Lin, Yang Cao, Qunsheng Ji, Qingyang Gu, Yujing Cheng, Zai Chang, Wei Guo, Pengyuan Wang, Ivan Garcia-Bassets, Zhi John Lu*, Dong Wang*. Tissue-Specific Transcription Reprogramming Promotes Liver Metastasis of Colorectal Cancer. Cell Research, 2020, 30 :34-49 （影响因子46.297）

    5.  Kequan Lin, Lu Li, Yifei Dai, Huili Wang, Shuaishuai Teng, Xilinqiqige Bao, Zhi John Lu*, Dong Wang*. A comprehensive evaluation of connectivity methods for L1000 data. Briefings in Bioinformatics, 2020, 21: 2194–2205（影响因子13.994）

    6.  Wei Shao, Shasha Li, Lu Li, Kequan Lin, Xinhong Liu, Haiyan Wang, Huili Wang and Dong Wang*. Chemical genomics reveals inhibition of breast cancer lung metastasis by Ponatinib via c-Jun. Protein & Cell, 2019, 10(3):161-177.（影响因子15.328）

    7.  Shasha Li, Shuaishuai Teng, Junquan Xu, Guannan Su, Yu Zhang, Jianqing Zhao, Suwei Zhang, Haiyan Wang, Wenyan Qin, Zhi John Lu, Yong Guo, Qianyong Zhu*, Dong Wang*. Microarray is an efficient tool for circRNA profiling. Briefings in Bioinformatics, 2019, 20 :1420-1433. （影响因子13.994）

    8.  Dong Wang#, Ivan Garcia-Bassets#, Chris Benner#, Wenbo Li, Xue Su, Yiming Zhou,Jinsong Qiu, Wen Liu, Minna U. Kaikkonen, Kenneth A. Ohgi, Christopher K. Glass, Michael G. Rosenfeld and Xiang-Dong Fu. Reprogramming transcription via distinct classes of enhancers functionally defined by eRNA. Nature, 2011, 474:390–394. (#These authors contributed equally to this work). （影响因子69.504）