一、个人简介

谢晓芳，博士，副研究员，硕士研究生导师，西南特色中药资源国家重点实验室教师。任世界中医药学会联合会道地药材多维评价专业委员会理事，中华中医药学会方药量效研究分会委员、四川省环境诱变剂学会理事、四川省实验动物学会理事。

主讲本科课程《中药毒理学》、《药理学实验》、《系统中药学》；研究生课程《中药毒理学专论》、《现代药理研究方法与实践》。研究方向：中药药效和毒理应用研究。近年来先后承担四川省科技厅、四川省中医药管理局等项目6项，参研国家自然科学基金重大、重点项目、国家科技支撑计划项目、国家“973”计划等项目20余项，参研完成中药复方新药品种7个，获四川省科技进步奖一等奖1项（排名第9）、教育部高等学校研究优秀成果奖（科学技术）科技进步二等奖1项（排名第3）、华夏医学科技进步二等奖1项（排名第4），公开发表学术论文140余篇，其中第一作者或通讯作者50篇，参编著作和教材12部。

二、代表性成果

1. Xin Xu^#, Xiaofang Xie^#, Huiqiong Zhang, Pei Wang, Gangmin Li, Junren Chen, Guanru Chen, Xiaoyu Cao, Liang Xiong, Fu Peng^*, Cheng Peng^*. Water-soluble alkaloids extracted from Aconiti Radix lateralis praeparata protect against chronic heart failure in rats via a calcium signaling pathway. Biomed Pharmacother. 2021, 135: 111184.

2. Liu Xingyu, Xie Xiaofang^*, Luo Maozhu, Zhao Yuting, Li Mengting, Peng Fu^*, Peng Cheng^*. The synergistic compatibility mechanisms of fuzi against chronic heart failure in animals: A systematic review and meta-analysis. Frontiers in Pharmacology, 2022,13. DOI: 10.3389/fphar.2022. 954253

3. Chen, Guanru^#, Xie, Xiaofang^#, Peng, Fu^*, Wang, Tianzhixin, Chen, Junren, Li, Gangmin, Liu, Juan, Peng, Cheng^*. Protective effect of the combination of essential oil from patchouli and tangerine peel against gastric ulcer in rats. Journal of Ethnopharmacology, 2021, 282:114645

4. Mengting Li^#, Xiaofang Xie^#, Haimei Chen, Qiuyun Xiong, Rongsheng Tong, Cheng Peng^*, Fu Peng^*. Aconitine induces cardiotoxicity through regulation of calcium signaling pathway in zebrafish embryos and in H9c2 cells. J Appl Toxicol. 2020, 40(6): 780-793.

5. Gang Min Li^#, Jun Ren Chen^#, Hui Qiong Zhang, Chen Sun 2, Guan Ru Chen, Qiu Yun Xiong, Xiao Yu Cao, Lei Yu, Zi Wei Lin, Jun Yuan Qin, Liu Jun Wu, Jing Li, Lin Pu, Fu Peng^*, Xiao Fang Xie^*, Cheng Peng^*. Rhein activated Fas-induced apoptosis pathway causing cardiotoxicity in vitro and in vivo. Toxicol Lett., 2022, 363: 67-76.

6. Xin Xu^#, Xiao-Fang Xie^#,Yan-Hong Dong, Hui-Qiong Zhang, Cheng Peng^*. Ginsenoside Rg1 Reduces Cardiotoxicity While Increases Cardiotonic Effect of Aconitine in vitro. Chin J Integr Med. 2022, 28(8): 693-701.

7. Huiqiong Zhang^#, Xiaofang Xie^#, Gangmin Li, Junren Chen, Mengting Li, Xin Xu, Qiuyun Xiong, Guanru Chen, Yanpeng Yin, Fu Peng^*, Yan Chen, Cheng Peng^*. Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo. Phytotherapy Research, 2021, 35: 4511-4525.

8. Junren Chen, Gangmin Li, Chen Sun, Fu Peng^*, Lei Yu, Yan Chen, Yuzhu Tan, Xiaoyu Cao, Yunli Tang, Xiaofang Xie^*, Cheng Peng^*. Chemistry, pharmacokinetics, pharmacological activities, and toxicity of Quercitrin. Phytother Res, 2022, 36(4):1545-1575.

9. Junyuan Qin, Junren Chen, Fu Peng^*, Chen Sun, Yu Lei, Guangru Chen, Gangming Li, Yanpeng Yin, Ziwei Lin, Liujun Wu, Jing Li, Wenxiu Liu, Cheng Peng^*, Xiaofang Xie^*. Pharmacological activities and pharmacokinetics of liquiritin: A review. J Ethnopharmacol. 2022, 293: 115257.doi: 10.1016/j.jep.2022.115257

10. Wen-Qing Li, Jing Li, Wen-Xiu Liu, Liu-Jun Wu, Jun-Yuan Qin, Zi-Wei Lin, Xin-Yu Liu, Shi-Yan Luo,Qing-Hua Wu^*, Xiao-Fang Xie^*, Cheng Peng^*. Isorhamnetin: A Novel Natural Product Beneficial for Cardiovascular Disease. Curr Pharm Des., 2022, 28(13): 2569-2582. doi: 10.2174/1381612828666220829113132.

11. 覃俊媛，孙晨，彭成，谢晓芳^*.赶黄草水煎液对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌生物膜形成的影响.中国抗生素杂志，2023，48（1）：54-61.

12. 张慧琼，李刚敏，陈俊仁，谢晓芳^*，熊亮，彭成^*.西洋参总皂苷联合顺铂对Luc-A549肺癌小鼠瘤体生长的影响.中药药理与临床，2021，37（3）：50-55.

13. 李刚敏，彭成，许欣，李静，谢晓芳^*.基于大鼠离体心脏的附子组分强心作用初探.时珍国医国药，2021，32（2）：265-268.

14. 熊秋韵，张慧琼，谢晓芳^*，刘怡，熊亮，邓青秀，彭成^*.附子不同炮制品对风湿寒痹类风湿性关节炎大鼠的急性毒性试验研究.中药药理与临床，2020，36（2）：149-158.

15. 余蕾，谢晓芳，彭芙，谢君，李梦婷，彭成*. 赶黄草总黄酮对活化的肝星状细胞TGF-β1/Smads信号通路的影响.天然产物研究与开发，2020，32：1118-1123.